When my kids were younger I would get up at 4 or 5am to brew. Take the kids to school at 8am or whatever and finish when I got back and then start work. In those days weekends were crazier than weekdays so I brewed during the week. There are any number of negatives about having all of your kids out of the house but there are some positives.
My issues are less kid induced and more self induced house projects. I do need to get back in the habit of brewing first thing or at night. Saves the rest of the day.