I've read that silicon dioxide can remove bitterness in wine. Have you noticed any changes in projected bitterness levels using Biofine in your IpA? I can get Kieselsol on our grain buys which is another branded name for silicon dioxide but have been hesitant to try it.
I have noticed no decreased bitterness in my IPA's nor has anyone that has had them said anything. The bitterness and hops are "crisper" but I attribute that to the lack of yeast in solution.